T2^Tg(H2K)1Art
Transgenic Allele Detail

Summary

• Symbol: T2^Tg(H2K)1Art
• Name: brachyury 2; transgene insertion 1, Karen Artzt
• MGI ID: MGI:1857754
• Synonyms: T2^Bob, T2^TgN(H2K)1Art
• Gene: T2 Location: Chr17:8574824-8642345 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: T2^Tg(H2K)1Art page

Transgene origin

• Strain of Origin: (CBA x B10.M-H2^f)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This mutation is the result of an approximately 200 kb transgene insertion between the last two exons of T2, coincident with a 3 kb deletion of intronic sequence. (J:29666, J:50797)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any T2 Mutation: 11 strains or lines available

References

• Original: J:29666 Rennebeck GM, et al., Is there a Brachyury the Second? Analysis of a transgenic mutation involved in notochord maintenance in mice. Dev Biol. 1995 Nov;172(1):206-17
• All: 3 reference(s)