Rce1^tm1Kim
Targeted Allele Detail

Summary

• Symbol: Rce1^tm1Kim
• Name: Ras converting CAAX endopeptidase 1; targeted mutation 1, Edward Kim
• MGI ID: MGI:1857763
• Synonyms: Rce1-
• Gene: Rce1 Location: Chr19:4672619-4675669 bp, - strand Genetic Position: Chr19, 4.07 cM
• Alliance: Rce1^tm1Kim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:53886
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The sequence encoding amino acids 115 through 329, the carboxy-terminal two-thirds of the protein, was replaced with a floxed neomycin selection cassette. The inserted cassette was not excised by cre-recombinase. (J:53886)

Expression

In Mice Carrying this Mutation:	39 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rce1 Mutation: 14 strains or lines available

References

• Original: J:53886 Kim E, et al., Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells. J Biol Chem. 1999 Mar 26;274(13):8383-90
• All: 4 reference(s)