Mc1r^taw
Spontaneous Allele Detail

Summary

• Symbol: Mc1r^taw
• Name: melanocortin 1 receptor; tawny
• MGI ID: MGI:1857788
• Gene: Mc1r Location: Chr8:124133846-124137483 bp, + strand Genetic Position: Chr8, 72.1 cM
• Alliance: Mc1r^taw page

Mutation origin

• Strain of Origin: M. m. molossinus

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele comprises a c.756G>T nucleotide substitution which causes the replacement of tryptophan at amino acid residue 252 with cysteine (p.W252C). (J:55617, J:98397)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mc1r Mutation: 44 strains or lines available

References

• Original: J:55617 Wada A, et al., Tawny: a novel light coat color mutation found in a wild population of Mus musculus molossinus, a new allele at the melanocortin 1 receptor (Mc1r) locus. Exp Anim. 1999 Apr;48(2):73-8
• All: 2 reference(s)