Pou4f3^ddl
Spontaneous Allele Detail

Summary

• Symbol: Pou4f3^ddl
• Name: POU domain, class 4, transcription factor 3; dreidel
• MGI ID: MGI:1857795
• Synonyms: ddl
• Gene: Pou4f3 Location: Chr18:42527662-42529158 bp, + strand Genetic Position: Chr18, 22.58 cM, cytoband B3-E1
• Alliance: Pou4f3^ddl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The molecular mutation of this allele is a TG dinucleotide deletion (nt #841-842 from GenBank accession number S69352) resulting in premature stop codon upstream of the POU box and homeodomains of the encoded protein. (J:55448)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pou4f3 Mutation: 25 strains or lines available

References

• Original: J:55448 Frankel WN, et al., The mutant mouse dreidel (ddl) contains a mutation in the Pou4f3 gene. Personal Communication. 1999
• All: 5 reference(s)