Pla2g2a^Mom1-r
Spontaneous Allele Detail

Summary

• Symbol: Pla2g2a^Mom1-r
• Name: phospholipase A2, group IIA (platelets, synovial fluid); modifier of Min1, tumor resistance
• MGI ID: MGI:1857820
• Synonyms: Mom-1, Mom1^R, sPLA2-IIA⁺
• Gene: Pla2g2a Location: Chr4:138559171-138562497 bp, + strand Genetic Position: Chr4, 70.57 cM
• Alliance: Pla2g2a^Mom1-r page

Mutation origin

• Strain of Origin: AKR/J

Mutation description

• Allele Type: Spontaneous
• Inheritance: Semidominant

Tumor Data

List all tumor models in MMHCdb carrying Pla2g2a^Mom1-r

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g2a Mutation: 7 strains or lines available

Notes

Other strains carrying the resistance allele include BALB, SWR, DBA, MA/MyJ, CAST/Ei, and C3H/HeN.

References

• Original: J:15703 Dietrich WF, et al., Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell. 1993 Nov 19;75(4):631-9
• All: 23 reference(s)