Hoxb1^tm1Ipc
Targeted Allele Detail

Summary

• Symbol: Hoxb1^tm1Ipc
• Name: homeobox B1; targeted mutation 1, Pierre Chambon
• MGI ID: MGI:1857823
• Synonyms: Hoxb1^3'RARE
• Gene: Hoxb1 Location: Chr11:96256578-96259082 bp, + strand Genetic Position: Chr11, 59.86 cM
• Alliance: Hoxb1^tm1Ipc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:46973
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted
• Mutation: Nucleotide substitutions
• Mutation details: Four base pair mutations were introduced into the retinoic acid responsive element located in the 3' flanking region of the gene. (J:46973)

Expression

In Mice Carrying this Mutation:

51 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb1 Mutation: 24 strains or lines available

References

• Original: J:46973 Studer M, et al., Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development. 1998 Mar;125(6):1025-36
• All: 4 reference(s)