Fbxw4^Dac-2J
Spontaneous Allele Detail

Summary

• Symbol: Fbxw4^Dac-2J
• Name: F-box and WD-40 domain protein 4; dactylaplasia 2 Jackson
• MGI ID: MGI:1857834
• Gene: Fbxw4 Location: Chr19:45566693-45648751 bp, - strand Genetic Position: Chr19, 38.75 cM
• Alliance: Fbxw4^Dac-2J page

Mutation origin

• Strain of Origin: MRL/MpJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: This mutation has been characterized as a MusD family transposon insertion 7471 nucleotides long within a highly conserved region in intron 5. (J:57316, J:127601, J:133888)
• Inheritance: Semidominant

Disease models

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fbxw4 Mutation: 28 strains or lines available

References

• Original: J:57316 Sidow A, et al., A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nat Genet. 1999 Sep;23(1):104-7
• All: 3 reference(s)