Lhx1^tm1Bhr
Targeted Allele Detail

Summary

• Symbol: Lhx1^tm1Bhr
• Name: LIM homeobox protein 1; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:1857848
• Synonyms: Lim^-, Lim1^-, Lim^delta
• Gene: Lhx1 Location: Chr11:84409110-84416361 bp, - strand Genetic Position: Chr11, 51.31 cM
• Alliance: Lhx1^tm1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:24115
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic fragment containing the entire coding region of the gene was replaced with a neomycin selection cassette. (J:24115)

Expression

In Mice Carrying this Mutation:	158 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lhx1 Mutation: 22 strains or lines available

References

• Original: J:24115 Shawlot W, et al., Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
• All: 21 reference(s)