Ap3b1^pe-11J
Spontaneous Allele Detail

Summary

• Symbol: Ap3b1^pe-11J
• Name: adaptor-related protein complex 3, beta 1 subunit; pearl 11 Jackson
• MGI ID: MGI:1857892
• Gene: Ap3b1 Location: Chr13:94495468-94702825 bp, + strand Genetic Position: Chr13, 49.22 cM
• Alliance: Ap3b1^pe-11J page

Mutation origin

• Strain of Origin: B10.RIII-H2^r/(71NS)SnJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• The molecular lesion in pe^11J has not yet been resolved.
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ap3b1 Mutation: 96 strains or lines available

Notes

This remutation arose spontaneously on the B10.RIII-H2r(71NS)/Sn strain. Homozygotes have lighter eye color at birth and a diluted gray coat color not different from the original pearl allele. Both homozygous males and females are fertile, and females are good mothers. Mice from this strain were not tested for differences in lysosomal enzymes or for platelet storage pool deficiency, both of which are common in other Ap3b1 mutations. DNA was saved from this remutation (J:51014, J:51188)

References

• Original: J:51014 Donahue LR, The Jackson Laboratory Mouse Mutant Resource 1999 Mutation Reports. MGI Direct Data Submission. 1999
• All: 2 reference(s)