Hsp90ab1^{Gt(pGT1.8geo)1Pgr}
Gene trapped Allele Detail

Summary

• Symbol: Hsp90ab1^{Gt(pGT1.8geo)1Pgr}
• Name: heat shock protein 90 alpha (cytosolic), class B member 1; gene trap 1, Peter Gruss
• MGI ID: MGI:1857893
• Synonyms: Hsp90beta^gt
• Gene: Hsp90ab1 Location: Chr17:45878704-45884187 bp, - strand Genetic Position: Chr17, 22.59 cM
• Alliance: Hsp90ab1^{Gt(pGT1.8geo)1Pgr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58075
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector pGT1.1geo, which contains a beta-geo cassette, inserted into intron 9. The absence of transcript expression was confirmed by northern blot analysis on E9.5 embryo extracts. (J:58075)

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hsp90ab1 Mutation: 46 strains or lines available

References

• Original: J:47982 Voss AK, et al., Efficiency assessment of the gene trap approach. Dev Dyn. 1998 Jun;212(2):171-80
• All: 3 reference(s)