Oca2^p-12DTR
Radiation induced Allele Detail

Summary

• Symbol: Oca2^p-12DTR
• Name: oculocutaneous albinism II; pink-eyed dilution 12DTR
• MGI ID: MGI:1857920
• Synonyms: dark pink-eyed, Herc2^p-12DTR, Oca2^p-106R, p^12DTR, p^xjl
• Gene: Oca2 Location: Chr7:55889508-56186266 bp, + strand Genetic Position: Chr7, 33.44 cM
• Alliance: Oca2^p-12DTR page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Deletion
• Oca2^p-12DTR involves 2 genes/genome features (Herc2, Oca2) View all
• Mutation details: In combination with Oca2^p this allele shows partial complementation of coat color. In addition an RT-PCR assay identified an intragenic Herc2 deletion removing ~5-kb of coding sequence. (J:56827, J:100221)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Oca2 Mutation: 70 strains or lines available

References

• Original: J:29903 Russell LB, et al., Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse. Genetics. 1995 Dec;141(4):1547-62
• All: 4 reference(s)