Cdx2^tm1Fbe
Targeted Allele Detail

Summary

• Symbol: Cdx2^tm1Fbe
• Name: caudal type homeobox 2; targeted mutation 1, F Beck
• MGI ID: MGI:1857928
• Synonyms: Cdx2-
• Gene: Cdx2 Location: Chr5:147237710-147244059 bp, - strand Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
• Alliance: Cdx2^tm1Fbe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:38772
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neomycin resistance cassette replaced 5.9 kb of the gene. (J:38772)

Expression

In Mice Carrying this Mutation:	107 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Cdx2^tm1Fbe

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdx2 Mutation: 22 strains or lines available

References

• Original: J:38772 Chawengsaksophak K, et al., Homeosis and intestinal tumours in Cdx2 mutant mice. Nature. 1997 Mar 6;386(6620):84-7
• All: 30 reference(s)