Hoxd10^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxd10^tm1Mrc
• Name: homeobox D10; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:1857962
• Synonyms: Hoxd-10^-
• Gene: Hoxd10 Location: Chr2:74522268-74525449 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd10^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:44765
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette disrupted exon 2 of the gene. (J:44765)

Expression

In Mice Carrying this Mutation:	64 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd10 Mutation: 15 strains or lines available

References

• Original: J:44765 Carpenter EM, et al., Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development. 1997 Nov;124(22):4505-14
• All: 7 reference(s)