Hoxd11^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxd11^tm1Mrc
• Name: homeobox D11; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:1857963
• Gene: Hoxd11 Location: Chr2:74509902-74517360 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd11^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:19630
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin cassette was inserted into sequences encoding the homeobox domain. (J:19630)

Expression

In Mice Carrying this Mutation:	55 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd11 Mutation: 14 strains or lines available

References

• Original: J:19630 Davis AP, et al., Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development. 1994 Aug;120(8):2187-98
• All: 16 reference(s)