Hoxd12^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxd12^tm1Mrc
• Name: homeobox D12; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:1857964
• Synonyms: d-12 (-), hoxd-12^-
• Gene: Hoxd12 Location: Chr2:74505357-74508049 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd12^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:32603
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin cassette was inserted into sequences encoding the homeobox domain. (J:32603)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd12 Mutation: 14 strains or lines available

References

• Original: J:32603 Davis AP, et al., A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse. Development. 1996 Apr;122(4):1175-85
• All: 1 reference(s)