Hoxa2^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxa2^tm1Mrc
• Name: homeobox A2; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:1858003
• Synonyms: Hoxa2^-
• Gene: Hoxa2 Location: Chr6:52139397-52141811 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa2^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58093
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into the homeobox domain of the gene. (J:58093)

Expression

In Mice Carrying this Mutation:	72 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa2 Mutation: 21 strains or lines available

References

• Original: J:58093 Barrow JR, et al., Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants. Development. 1999 Nov;126(22):5011-26
• All: 2 reference(s)