Krt19^tm1(cre)Mmt
Targeted Allele Detail

Summary

• Symbol: Krt19^tm1(cre)Mmt
• Name: keratin 19; targeted mutation 1, Makoto M Taketo
• MGI ID: MGI:1858007
• Synonyms: Ck19:Cre, K19^cre, Krt1-19^cre
• Gene: Krt19 Location: Chr11:100031636-100036752 bp, - strand Genetic Position: Chr11, 63.42 cM
• Alliance: Krt19^tm1(cre)Mmt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58367
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Krt19^tm1(cre)Mmt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt19 (MGI:96693)

• Mutation details: The allele was generated by insertion of the cre coding sequence and a PGK-neomycin resistance cassette into the translation initiation site and deletion of 365 bp of exon 1. (J:58367)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt19 (mouse) Summary of all recombinase alleles driven by Krt19. Comparative matrix view of recombinase activities Alliance mouse Krt19 gene page

Expression

In Mice Carrying this Mutation:

72 assay results 2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Krt19^tm1(cre)Mmt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt19 Mutation: 21 strains or lines available

References

• Original: J:58367 Harada N, et al., Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 1999 Nov 1;18(21):5931-42
• All: 20 reference(s)