Epo^tm1Jae
Targeted Allele Detail

Summary

• Symbol: Epo^tm1Jae
• Name: erythropoietin; targeted mutation 1, Rudolf Jaenisch
• MGI ID: MGI:1858038
• Synonyms: Epo-
• Gene: Epo Location: Chr5:137481282-137484078 bp, - strand Genetic Position: Chr5, 76.5 cM, cytoband G
• Alliance: Epo^tm1Jae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:29254
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced a genomic fragment containing exons 2-5, which contain most of the coding region. (J:29254)

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epo Mutation: 31 strains or lines available

References

• Original: J:29254 Wu H, et al., Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 1995 Oct 6;83(1):59-67
• All: 6 reference(s)