Atp7a^Mo-Xm
Spontaneous Allele Detail

Summary

• Symbol: Atp7a^Mo-Xm
• Name: ATPase, copper transporting, alpha polypeptide; mottled Xm
• MGI ID: MGI:1858104
• Synonyms: Xmo6^1R
• Gene: Atp7a Location: ChrX:105070882-105168532 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Atp7a^Mo-Xm page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: A spontaneous mutation that arose at the Oak Ridge National Laboratory. The mottled Xm mutant showed strongly reduced levels of Atp7a transcript.
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp7a Mutation: 69 strains or lines available

Notes

Atp7a^Mo-Xm. This spontaneous mutation is an embryonic lethal in hemizygous males. Heterozygous females produce a reduced level of Atp7a transcript (J:38977).

References

• Original: J:38977 Cecchi C, et al., The mottled mouse as a model for human Menkes disease: identification of mutations in the Atp7a gene. (Correction: vol. 6(5):829). Hum Mol Genet. 1997 Mar;6(3):425-33
• All: 1 reference(s)