Hba^th-J
Chemically induced Allele Detail

Summary

• Symbol: Hba^th-J
• Name: hemoglobin alpha chain complex; alpha thalassemia Jackson
• MGI ID: MGI:1858115
• Synonyms: alpha^MD
• Gene: Hba Location: unknown Genetic Position: Chr11, cytoband A

Mutation origin

• Strain of Origin: C57BL/6J x Triethyllenemelamine-treated male

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intergenic deletion
• Hba^th-J involves 6 genes/genome features (Rhbdf1, Mpg, Nprl3 ...) View all
• Mutation details: This mutation was shown to be a deletion that included the Hba-x, Hba-a1 and Hba-a2 genes (J:32654). The Mpg, Rhbdf1 and Phg genes are also included in the deletion region (J:29665). (J:29665, J:32654)
• Inheritance: Codominant

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hba Mutation: 10 strains or lines available

Notes

The mutation was induced in a male mouse by triethyllenemelamine.

References

• Original: J:45721 Whitney JB, et al., New mutants and biochemical variants: Alpha thalassemia. Mouse News Lett. 1978;58:47-48
• All: 12 reference(s)