Spta1^sph-2J
Spontaneous Allele Detail

Summary

• Symbol: Spta1^sph-2J
• Name: spectrin alpha, erythrocytic 1; spherocytosis 2 Jackson
• MGI ID: MGI:1858128
• Synonyms: sph^2J
• Gene: Spta1 Location: Chr1:174000342-174076016 bp, + strand Genetic Position: Chr1, 80.97 cM
• Alliance: Spta1^sph-2J page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Spontaneous
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spta1 Mutation: 147 strains or lines available

Notes

Spna1^sph-2J, spherocytosis-2J, recessive. This mutation arose in the C3HeB/FeJ strain. It resembles Spna1^sph in the absence of a-spectrin in the red cell membrane skeleton (J:12205) . This allele is extinct (J:88022).

References

• Original: J:7501 Bodine DM 4th, et al., Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes. Cell. 1984 Jul;37(3):721-9
• All: 3 reference(s)