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tks1
Spontaneous Allele Detail
Summary
Symbol: tks1
Name: t-complex; t, Kansas State 1
MGI ID: MGI:1858139
Gene: t  Location: unknown  Genetic Position: Chr17, Syntenic
Alliance: tks1 page
Mutation
origin
Strain of Origin:  STOCK T Itpr3tf/tw5+
Mutation
description
Allele Type:    Spontaneous
Mutation:    Other
 
Mutation detailsThis t haplotype resulted from a rare recombination event between haplotype tw5 and a wild-type chromosome. DNA probes obtained by microdissection and microcloning of fragments of mouse Chromosome 17 show that this allele comprises a deletion of D17Leh54, 94, 180 and 443, and a duplication of D17Leh89, 467,and 525. This haplotype is a member of the t9 complementation group and, although derived from tw5, it is not found in wild mouse populations. (J:8922)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any t Mutation:  19 strains or lines available
References
Original:  J:8922 Bucan M, et al., Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex. Genes Dev. 1987 Jun;1(4):376-85
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory