Myo5a^flr
Spontaneous Allele Detail

Summary

• Symbol: Myo5a^flr
• Name: myosin VA; flailer
• MGI ID: MGI:1858520
• Synonyms: flail, flr, tb^2J
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^flr page

Mutation origin

• Strain of Origin: C57BL/10J

Mutation description

• Allele Type: Spontaneous
• Mutation: Other
• Mutation details: Hybrid. This mutation is caused by gene shuffling between Gnb5 and Myo5a. The shuffling combines the promoter of the first two exons of Gnb5 with the C-terminal exons of Myo5a. Flailer homozygotes express transcripts of three genes: wild-type Gnb5, wild-type Myo5a and the flailer hybrid gene. (J:61324)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 265 strains or lines available

References

• Original: J:79827 The Jackson Laboratory Office of Genetic Resources, Registry of Remutation at The Jackson Laboratory. MGI Direct Data Submission. 1973
• All: 6 reference(s)