Tert^tm1Fish
Targeted Allele Detail

Summary

• Symbol: Tert^tm1Fish
• Name: telomerase reverse transcriptase; targeted mutation 1, Fuyuki Ishikawa
• MGI ID: MGI:1859741
• Synonyms: mTERT-
• Gene: Tert Location: Chr13:73775030-73797962 bp, + strand Genetic Position: Chr13, 40.12 cM
• Alliance: Tert^tm1Fish page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:59858
• Parent Cell Line: JH1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of three exons, encoding a highly conserved motif A, with a neomycin cassette. (J:59858)

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tert Mutation: 55 strains or lines available

References

• Original: J:59858 Yuan X, et al., Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice. Genes Cells. 1999 Oct;4(10):563-72
• All: 12 reference(s)