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Tal1Hpt
Spontaneous Allele Detail
Summary
Symbol: Tal1Hpt
Name: T cell acute lymphocytic leukemia 1; hair patches
MGI ID: MGI:1859843
Synonyms: Hpa
Gene: Tal1  Location: Chr4:114913623-114928952 bp, + strand  Genetic Position: Chr4, 52.73 cM
Alliance: Tal1Hpt page
Tal1Hpt/+

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  (C57BL/6J x C3FeLe.B6-a/a)F1
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsAn endogenous retroviral class II intracisternal A particle (IAP) inserted into intron 4. Quantitative real time PCR revealed differential expression of one gene in the interval, T-cell acute lymphocytic leukemia 1 (Tal1), which was highly expressed in kidney and skin.
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Tal1 Mutation:  33 strains or lines available
References
Original:  J:13897 Lane PW, Hair patches. Mouse News Lett. 1981;65:27
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory