Dst^dt-alb
Spontaneous Allele Detail

Summary

• Symbol: Dst^dt-alb
• Name: dystonin; dystonia musculorum Albany
• MGI ID: MGI:1859982
• Synonyms: dt-Alb, dt^Alb
• Gene: Dst Location: Chr1:33947306-34347742 bp, + strand Genetic Position: Chr1, 12.91 cM
• Alliance: Dst^dt-alb page

Mutation origin

• Strain of Origin: BALB/cByJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Other
• Mutation details: Exons 12 throught 46 cannot be detected by PCR and are likely deleted, with the possibility of a large DNA insertion in their place. Northern blot analysis of brain RNA derived from homozygous mice demonstrated that an aberrant smaller transcript was expressed from this allele. Southern blot analysis indicated that a deletion or rearrangement of part of the gene had occurred in mutant mice. (J:26733, J:104061, J:120587)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dst Mutation: 557 strains or lines available

References

• Original: J:64441 Messer A, Dst^dt-alb - dystonia musculorum-Albany. Mouse News Lett. 1978;59:39
• All: 9 reference(s)