Myo5a^d-n2J
Spontaneous Allele Detail

Summary

• Symbol: Myo5a^d-n2J
• Name: myosin VA; dilute neurological 2 Jackson
• MGI ID: MGI:1860204
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^d-n2J page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Genomic sequence analysis revealed that this allele was the result of a G-to-T transversion in the first base of intron 37 that eliminates exon 37 splice donor site by changing it from G-GT to G-TT, resulting in four abnormal classes of mRNA transcripts. (J:47547)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 265 strains or lines available

References

• Original: J:47547 Huang JD, et al., Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations. (Errata Genetics 1998 Nov;150:1331). Genetics. 1998 Apr;148(4):1963-72
• All: 1 reference(s)