Rr29^Hx
Spontaneous Allele Detail

Summary

• Symbol: Rr29^Hx
• Name: regulatory region 29; hemimelic extra toes
• MGI ID: MGI:1860897
• Synonyms: Shh^Hx
• Gene: Rr29 Location: Chr5:29519879-29520665 bp
• Alliance: Rr29^Hx page

Skeletal phenotypes of Rr29^Hx/Rr29^Hx and Rr29^Hxl3/Shh⁺ mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: B10.D2-Hc¹ H2^d H2-T18^c/nSnJ

Mutation description

• Allele Type: Spontaneous (Modified regulatory region)
• Mutation: Single point mutation
• Rr29^Hx involves 1 genes/genome features (Lmbr1) View all
• Mutation details: This spontaneous mutation is the result of a G-to-A transition in a conserved Shh enhancer element located in intron 5 of the Lmbr1 gene. The mutation is located 145 bp 3' of the Hxl3 mutation. (J:84551, J:87798)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	38 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr29 Mutation: 2 strains or lines available

References

• Original: J:13476 Dickie MM, Hemimelic extra toes, Hx. Mouse News Lett. 1968;38:24
• All: 16 reference(s)