Lrp6^Cd
Spontaneous Allele Detail

Summary

• Symbol: Lrp6^Cd
• Name: low density lipoprotein receptor-related protein 6; crooked
• MGI ID: MGI:1861309
• Synonyms: crooked tail
• Gene: Lrp6 Location: Chr6:134423439-134543876 bp, - strand Genetic Position: Chr6, 65.37 cM
• Alliance: Lrp6^Cd page

Skeletal abnormalities of the Lrp6^Cd/Lrp6^Cd mouse

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: A

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: A single nucleotide substitution was found in exon 7 which results in a G494D conversion in the second YWTD-EGF repeat domain. (J:101423)
• Inheritance: Semidominant

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrp6 Mutation: 95 strains or lines available

References

• Original: J:13045 Morgan WC, A new crooked tail mutation involving distinctive pleiotropism. J Genet. 1954;52(2):354-373
• All: 10 reference(s)