Krd
Transgenic Allele Detail

Summary

• Symbol: Krd
• Name: kidney and retinal defects
• MGI ID: MGI:1861657
• Synonyms: Tg8052
• Gene: Krd Location: unknown Genetic Position: Chr19, Syntenic
• Alliance: Krd page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic
• Mutations: Insertion, Intergenic deletion
• Krd involves 4 genes/genome features (Hps1, Pkd2l1, Scd1 ...) View all
• Mutation details: The phenotype of this mouse has been attributed to a 7 cM transgene induced deletion, Del(19)TgN8052Mm, which includes the Pax2 and Pkd2l1. The transgene inserted into a LINE element in the distal region of Chromosome 19. The Scd1 and pale ear Hps1 genes are also deleted in Del(19)TgN8052Mm mice, along with several D19Mit markers. (J:20807, J:50327, J:54055)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Krd Mutation: 1 strain or line available

References

• Original: J:20807 Keller SA, et al., Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus. Genomics. 1994 Sep 15;23(2):309-20
• All: 7 reference(s)