Gsdma3^Rim3
Spontaneous Allele Detail

Summary

• Symbol: Gsdma3^Rim3
• Name: gasdermin A3; recombination induced mutation 3
• MGI ID: MGI:1861663
• Gene: Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
• Alliance: Gsdma3^Rim3 page

Mutation origin

• Strain of Origin: H2^wm7 x B10.MOL-SGR x B10.H2

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A single base c.1042>A substitution results in an alanine to threonine amino acid residue change at position 348 (p.A348T). Introduction into wild-type mice of BAC clones engineered to carry this mutation results in an identical phenotype to that of mice with this allele. (J:122738)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gsdma3 Mutation: 26 strains or lines available

References

• Original: J:3639 Shiroishi T, et al., III. Mammalian genetics. Mouse visible mutations of the intra-MHC recombinants. Annu Rep Natl Inst Genet Jpn. 1992;42:49
• All: 3 reference(s)