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Is(In8B2-8B3.1;6C1)1Tshir
Spontaneous Allele Detail
Summary
Symbol: Is(In8B2-8B3.1;6C1)1Tshir
Name: Insertion, Chr8 B2-B3.1 into Chr 6C1, Toshihiko Shiroishi 1; Insertion, Chr 8 B2-B3.1 into Chr 6 C1, Toshihiko Shiroishi 1
MGI ID: MGI:1861689
Synonyms: Rim4
Gene: Is(In8B2-8B3.1;6C1)1Tshir  Location: Chr6:68125501-74184556 bp  Genetic Position: Chr6, Syntenic
Mutation
origin
Strain of Origin:  B10.MOL-SGR x B10.A
Mutation
description
Allele Type:    Spontaneous
Mutations:    Insertion, Translocation
 
Mutation detailsBase position 72,155,439 (build 37) of Chr6 is fused to base position 65,296,826 of Chr8 in the proximal junction in Chr6 and base position 58,788,949 of Chr8 is fused to base position 72,159,653 of Chr6 in the distal junction. The physical length of the insertion fragment is 6.5 Mb corresponding to Chr8 band 8B2 to 8B3.1. The insertion in Chr 6 is in band 6C1. (J:198239)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 9 assay results
In Structures Affected by this Mutation: 16 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Is(In8B2-8B3.1;6C1)1Tshir Mutation:  1 strain or line available
References
Original:  J:3639 Shiroishi T, et al., III. Mammalian genetics. Mouse visible mutations of the intra-MHC recombinants. Annu Rep Natl Inst Genet Jpn. 1992;42:49
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory