Ntf3^tm2Jae
Targeted Allele Detail

Summary

• Symbol: Ntf3^tm2Jae
• Name: neurotrophin 3; targeted mutation 2, Rudolf Jaenisch
• MGI ID: MGI:1861706
• Synonyms: Nt-3^2lox, NT3^flx, Ntf3^lox
• Gene: Ntf3 Location: Chr6:126078375-126143703 bp, - strand Genetic Position: Chr6, 60.45 cM
• Alliance: Ntf3^tm2Jae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52951
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Introduction of loxP sites flanking exon 2 of the Ntf3 gene. (J:52951)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntf3 Mutation: 24 strains or lines available

References

• Original: J:52951 Bates B, et al., Neurotrophin-3 is required for proper cerebellar development. Nat Neurosci. 1999 Feb;2(2):115-7
• All: 16 reference(s)