F3^tm1Gjb
Targeted Allele Detail

Summary

• Symbol: F3^tm1Gjb
• Name: coagulation factor III; targeted mutation 1, George J Bronze, Jr
• MGI ID: MGI:1861745
• Synonyms: TF-
• Gene: F3 Location: Chr3:121517186-121528697 bp, + strand Genetic Position: Chr3, 52.94 cM
• Alliance: F3^tm1Gjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35037
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into exon 3. (J:35037)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any F3 Mutation: 24 strains or lines available

References

• Original: J:35037 Toomey JR, et al., Targeted disruption of the murine tissue factor gene results in embryonic lethality. Blood. 1996 Sep 1;88(5):1583-7
• All: 5 reference(s)