Dll1^tm1Gos
Targeted Allele Detail

Summary

• Symbol: Dll1^tm1Gos
• Name: delta like canonical Notch ligand 1; targeted mutation 1, Achim Gossler
• MGI ID: MGI:1861919
• Synonyms: Dll1-, Dll1^lacZ
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^tm1Gos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:39633
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: In-frame insertion of a LacZ-PGK-neomycin resistance cassette replaced sequences that code for amino acids 2-116 of the Dll1 gene. (J:39633)

Expression

In Mice Carrying this Mutation:	370 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:39633 Hrabe de Angelis M, et al., Maintenance of somite borders in mice requires the Delta homologue DII1. Nature. 1997 Apr 17;386(6626):717-21
• All: 60 reference(s)