Mdm4^{Gt(VICTR20)7Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mdm4^{Gt(VICTR20)7Lex}
• Name: transformed mouse 3T3 cell double minute 4; gene trap 7, Lexicon Genetics
• MGI ID: MGI:1861977
• Synonyms: Mdm4-null, Mdm4^tm1Lex, mdmx¹
• Gene: Mdm4 Location: Chr1:132913843-132958325 bp, - strand Genetic Position: Chr1, 57.75 cM, cytoband G-G
• Alliance: Mdm4^{Gt(VICTR20)7Lex} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77907
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector insertion is near the 5'-end of the coding region of the gene, 1-2 codons downstream of the ATG start site. (J:77030)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Mdm4^{Gt(VICTR20)7Lex}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdm4 Mutation: 193 strains or lines available

References

• Original: J:46940 Zambrowicz BP, et al., Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature. 1998 Apr 9;392(6676):608-11
• All: 10 reference(s)