Chd7^Dz
Chemically induced Allele Detail

Summary

• Symbol: Chd7^Dz
• Name: chromodomain helicase DNA binding protein 7; dizzy
• MGI ID: MGI:1862009
• Synonyms: Dz, Gena47, GENA 47
• Gene: Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
• Alliance: Chd7^Dz page

Mutation origin

• Strain of Origin: BALB/cOlaHsd

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A c.5536G>T transversion in exon 27 resulted in a p.E1846* nonsense mutation. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Chd7 Mutation: 138 strains or lines available

References

• Original: J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
• All: 3 reference(s)