Pmp22^Tr-1H
Chemically induced Allele Detail

Summary

• Symbol: Pmp22^Tr-1H
• Name: peripheral myelin protein 22; trembler 1 Harwell
• MGI ID: MGI:1862010
• Synonyms: Gena51, GENA 51, H12R, Tr-m1H
• Gene: Pmp22 Location: Chr11:63019808-63050373 bp, + strand Genetic Position: Chr11, 38.99 cM
• Alliance: Pmp22^Tr-1H page

Mutation origin

• Strain of Origin: BALB/cAnNCrl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele involves an A to G transition at position 35 in codon 12 producing a histidine to arginine substitution. (J:63755)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pmp22 Mutation: 33 strains or lines available

References

• Original: J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
• All: 3 reference(s)