Celsr1^Scy
Chemically induced Allele Detail

Summary

• Symbol: Celsr1^Scy
• Name: cadherin, EGF LAG seven-pass G-type receptor 1; spin cycle
• MGI ID: MGI:1862019
• Synonyms: Gena 175, GENA175, Scy
• Gene: Celsr1 Location: Chr15:85783130-85918404 bp, - strand Genetic Position: Chr15, 40.42 cM
• Alliance: Celsr1^Scy page

Mutation origin

• Strain of Origin: BALB/cAnNCrl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T-to-A point mutation at nucleotide 3337 was induced by ENU mutagenesis. The mutation results in an asparagine to lysine substitution at codon 1110 which forms part of the linker region connecting adjacent cadherin domains. (J:84285)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Celsr1 Mutation: 146 strains or lines available

References

• Original: J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
• All: 4 reference(s)