Lhx9^tm1Lmgd
Targeted Allele Detail

Summary

• Symbol: Lhx9^tm1Lmgd
• Name: LIM homeobox protein 9; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
• MGI ID: MGI:1888554
• Synonyms: Lhx9^-
• Gene: Lhx9 Location: Chr1:138752924-138776315 bp, - strand Genetic Position: Chr1, 60.82 cM, cytoband G-H2
• Alliance: Lhx9^tm1Lmgd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:60621
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 and 3 of the gene, which encode the first and second LIM domains of the protein. (J:60621)

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lhx9 Mutation: 31 strains or lines available

References

• Original: J:60621 Birk OS, et al., The LIM homeobox gene Lhx9 is essential for mouse gonad formation. Nature. 2000 Feb 24;403(6772):909-13
• All: 3 reference(s)