Tcf21^tm1Eno
Targeted Allele Detail

Summary

• Symbol: Tcf21^tm1Eno
• Name: transcription factor 21; targeted mutation 1, Eric N Olson
• MGI ID: MGI:1888738
• Synonyms: capsulin^-, Tcf21^LacZ
• Gene: Tcf21 Location: Chr10:22693162-22696042 bp, - strand Genetic Position: Chr10, 10.33 cM
• Alliance: Tcf21^tm1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64068
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of the first exon with a neomycin resistance cassette. (J:64068)

Expression

In Mice Carrying this Mutation:	6 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf21 Mutation: 16 strains or lines available

References

• Original: J:64068 Lu J, et al., The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9525-30
• All: 5 reference(s)