Tapbp^tm1Luc
Targeted Allele Detail

Summary

• Symbol: Tapbp^tm1Luc
• Name: TAP binding protein; targeted mutation 1, Luc van Kaer
• MGI ID: MGI:1888941
• Synonyms: Tpn^-
• Gene: Tapbp Location: Chr17:34138452-34148264 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Tapbp^tm1Luc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64177
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Insertion of a neomycin resistance cassette into the fourth exon. (J:64177)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tapbp Mutation: 24 strains or lines available

References

• Original: J:64177 Grandea AG 3rd, et al., Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity. 2000 Aug;13(2):213-22
• All: 10 reference(s)