Mdga2^Adp
Transgenic Allele Detail

Summary

• Symbol: Mdga2^Adp
• Name: MAM domain containing glycosylphosphatidylinositol anchor 2; acrodysplasia
• MGI ID: MGI:1889308
• Gene: Mdga2 Location: Chr12:66512834-67269323 bp, - strand Genetic Position: Chr12, 27.63 cM
• Alliance: Mdga2^Adp page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2)F1

Transgene description

• Transgene Type: Transgenic
• Mutations: Insertion, Intragenic deletion
• Mutation details: 19 to 24 kb of intronic sequence between exons 3 and 4 was replaced with 6 to 7 copies of the pL116 transgene, which contained the entire bovine papilloma virus (BPV) genome, the human growth hormone-releasing factor gene (hGRF) driven by the mouse metallothionein I promoter and plasmid pMl2d sequences. (J:82720, J:181260)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdga2 Mutation: 76 strains or lines available

References

• Original: J:82720 DeLoia JA, et al., A transgene insertional mutation at an imprinted locus in the mouse genome. Dev Suppl. 1990;:73-9
• All: 3 reference(s)