Ph^e
Spontaneous Allele Detail

Summary

• Symbol: Ph^e
• Name: patch deletion region; patch extended
• MGI ID: MGI:1889551
• Gene: Ph Location: Chr5:75315348-75330641 bp Genetic Position: Chr5, Syntenic
• Alliance: Ph^e page

Mutation origin

• Strain of Origin: STOCK Ph

Mutation description

• Allele Type: Spontaneous
• Mutation: Deletion
• Ph^e involves 1 genes/genome features (Pdgfra) View all
• Mutation details: This allele comprises a deletion including the Pdgfra gene. Precise breakpoints have not been mapped, but does not extend into the coding sequences of the adjacent Kit gene. However, expression of a functional KIT protein is altered in these mutants. (J:52810)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ph Mutation: 1 strain or line available

Notes

Double heterozygotes of Ph^e with the closely linked genes Kit^W-v and Rw were different in color from those with Ph. In particular, Ph^e +/+ Kit^W-v mice resembled Kit^W-v homozygotes, and were sterile (J:5811).

References

• Original: J:5811 Truslove GM, A new allele at the patch locus in the mouse. Genet Res. 1977 Apr;29(2):183-6
• All: 3 reference(s)