Kcne1^pkr
Spontaneous Allele Detail

Summary

• Symbol: Kcne1^pkr
• Name: potassium voltage-gated channel, Isk-related subfamily, member 1; punk rocker
• MGI ID: MGI:1889639
• Gene: Kcne1 Location: Chr16:92142889-92156356 bp, - strand Genetic Position: Chr16, 53.57 cM
• Alliance: Kcne1^pkr page

Inner ear cross-sections of 3 month old Kcne1^pkr/Kcne1^pkr and Kcne1^pkr/⁺

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/10J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A C-to-T nucleotide substitution in the third exon causes an arginine to be altered to a termination codon at amino acid position 67 (p.R67*). (J:64772)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcne1 Mutation: 13 strains or lines available

References

• Original: J:64772 Letts VA, et al., A new spontaneous mouse mutation in the kcne1 gene. Mamm Genome. 2000 Oct;11(10):831-5
• All: 2 reference(s)