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Tg(BCL2)1Tsk
Transgene Detail
Summary
Symbol: Tg(BCL2)1Tsk
Name: transgene insertion 1, Thomas S Kupper
MGI ID: MGI:1891501
Synonyms: K14/Bcl-2
Transgene: Tg(BCL2)1Tsk  Location: unknown  
Alliance: Tg(BCL2)1Tsk page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(BCL2)1Tsk expresses 1 gene
 
Mutation detailsTransgenic mice overexpress human BCL2 gene in basal epidermis and root sheath. The transgene is driven by human keratin 14 promoter. (J:64948)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Two lines established, line 1 and line 7. Lines not distinguished by phenotype in publication.
References
Original:  J:64948 Muller-Rover S, et al., Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia. Am J Pathol. 2000 Apr;156(4):1395-405
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory