Ets2^tm1Rgo
Targeted Allele Detail

Summary

• Symbol: Ets2^tm1Rgo
• Name: E26 avian leukemia oncogene 2, 3' domain; targeted mutation 1, Robert G Oshima
• MGI ID: MGI:1891557
• Synonyms: Ets2^db, ets2^db1
• Gene: Ets2 Location: Chr16:95503274-95522093 bp, + strand Genetic Position: Chr16, 56.64 cM, cytoband C3-qter
• Alliance: Ets2^tm1Rgo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:47620
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• All or part of three exons encoding the DNA binding domain were replaced with pMC1NeoA. (J:43739)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Ets2^tm1Rgo

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ets2 Mutation: 39 strains or lines available

References

• Original: J:47620 Yamamoto H, et al., Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev. 1998 May 1;12(9):1315-26
• All: 14 reference(s)