Fgf7^tm1Efu
Targeted Allele Detail

Summary

• Symbol: Fgf7^tm1Efu
• Name: fibroblast growth factor 7; targeted mutation 1, Elaine Fuchs
• MGI ID: MGI:1891569
• Synonyms: FGF7-, Fgftm1Efu, KGF-
• Gene: Fgf7 Location: Chr2:125876578-125933105 bp, + strand Genetic Position: Chr2, 61.76 cM, cytoband F-G
• Alliance: Fgf7^tm1Efu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:31155
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Replacement of 205bp in exon 1 with a neomycin resistance cassette. (J:31155)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf7 Mutation: 17 strains or lines available

References

• Original: J:31155 Guo L, et al., Keratinocyte growth factor is required for hair development but not for wound healing. Genes Dev. 1996 Jan 15;10(2):165-75
• All: 16 reference(s)