Ndst2^tm1Lkj
Targeted Allele Detail

Summary

• Symbol: Ndst2^tm1Lkj
• Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; targeted mutation 1, Lena Kjellen
• MGI ID: MGI:1913285
• Synonyms: Ndst2-, NDST-2^-
• Gene: Ndst2 Location: Chr14:20773798-20784630 bp, - strand Genetic Position: Chr14, 11.53 cM, cytoband B
• Alliance: Ndst2^tm1Lkj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57121
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 307 base pairs of the 5'-untranslated region and 780 base pairs of the coding sequence was replaced by a PGK-neo cassette. (J:57121)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndst2 Mutation: 27 strains or lines available

References

• Original: J:57121 Forsberg E, et al., Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme [see comments]. Nature. 1999 Aug 19;400(6746):773-6
• All: 24 reference(s)