Tg(IGF1)1Jdg
Transgene Detail

Summary

• Symbol: Tg(IGF1)1Jdg
• Name: transgene insertion 1, John DiGiovanni
• MGI ID: MGI:1926378
• Synonyms: HK1.IGF-1
• Transgene: Tg(IGF1)1Jdg Location: unknown
• Alliance: Tg(IGF1)1Jdg page

Transgene origin

• Strain of Origin: (FVB x ICR)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IGF1)1Jdg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGF1 (3479)

  Igf1	(MGI:96432)

• Mutation details: Overexpression of human IGF1 in the epidermis of transgenic mice, driven by the human keratin 1 (KRT1) promoter. (J:39752)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Mouse line HI.5 established.

References

• Original: J:39752 Bol DK, et al., Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice. Oncogene. 1997 Apr 10;14(14):1725-34
• All: 1 reference(s)